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Moreover, Li et al. have discovered that the upregulation of PI3K/AKT pathway promotes the expressions of placental progress factor (PlGF) and C-X-C Motif Chemokine Ligand 1 (CXCL1) read more in lung cancer stem cells, which more stimulate angiogenesis [59]. CCPlenty of paracrine elements secreted by MSCs are ligands for receptors that activate PI3
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